Revelation 16:1-4

1And I heard a great voice out of the temple saying to the seven angels, Go your ways, and pour out the vials of the wrath of God upon the earth.

2And the first went, and poured out his vial upon the earth; and there fell a noisome and grievous sore upon the men which had the mark of the beast, and upon them which worshipped his image. 3And the second angel poured out his vial upon the sea; and it became as the blood of a dead man: and every living soul died in the sea. 4And the third angel poured out his vial upon the rivers and fountains of waters; and they became blood.