Revelation 16:10-13

10And the fifth angel poured out his vial upon the throne of the beast; and his kingdom was full of darkness; and they gnawed their tongues for pain, 11And blasphemed the God of heaven because of their pains and their sores, and repented not of their deeds.

12And the sixth angel poured out his vial upon the great river Euphrates; and its water was dried up, that the way of the kings of the east might be prepared. 13And I saw three unclean spirits like frogs come out of the mouth of the dragon, and out of the mouth of the beast, and out of the mouth of the false prophet.