Genesis 25:19-24

19This is the account of the family of Isaac, the son of Abraham.

20When Isaac was forty years old, he married Rebekah, the daughter of Bethuel the Aramean from Paddan-aram and the sister of Laban the Aramean.

21Isaac pleaded with the Lord on behalf of his wife, because she was unable to have children. The Lord answered Isaac’s prayer, and Rebekah became pregnant with twins.

22But the two children struggled with each other in her womb. So she went to ask the Lord about it. “Why is this happening to me?” she asked.

23And the Lord told her, “The sons in your womb will become two nations. From the very beginning, the two nations will be rivals. One nation will be stronger than the other; and your older son will serve your younger son.”

24And when the time came to give birth, Rebekah discovered that she did indeed have twins!