Genesis 6:4-7

4There were giants in the earth in those days; and also after that, when the sons of God came in unto the daughters of men, and they bare children to them, the same became mighty men which were of old, men of renown.

5And God saw that the wickedness of man was great in the earth, and that every imagination of the thoughts of his heart was only evil continually.12 6And it repented the Lord that he had made man on the earth, and it grieved him at his heart. 7And the Lord said, I will destroy man whom I have created from the face of the earth; both man, and beast, and the creeping thing, and the fowls of the air; for it repenteth me that I have made them.3