Revelation 16:2-4

2And the first went, and poured out his bowl into the earth; and it became a noisome and grievous sore upon the men that had the mark of the beast, and that worshipped his image.

3And the second poured out his bowl into the sea; and it became blood as of a dead man; and every living soul died, even the things that were in the sea.

4And the third poured out his bowl into the rivers and the fountains of the waters; and it became blood.